BDBM743827 5-{4-[(4-{5-chloro-4-[(1- methyl-2-oxo-1,2,3,4- tetrahydroquinolin-6- yl)amino]pyrimidin-2- yl}piperazin-1- yl)methyl]piperidin-1- yl}-2-(2,6- dioxopiperidin-3-yl)-2,3- dihydro-1H-isoindole- 1,3-dione::US12310975, Example 369

SMILES CN1C(=O)CCc2cc(Nc3nc(N4CCN(CC5CCN(c6ccc7c(c6)C(=O)N(C6CCC(=O)NC6=O)C7=O)CC5)CC4)ncc3Cl)ccc21

InChI Key InChIKey=QYSFWVAUNNUFAI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743827   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743827BDBM743827(5-{4-[(4-{5-chloro-4-[(1- methyl-2-oxo-1,2,3,4- te...)
Affinity DataIC50: 100nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent