BDBM743831 5-(2-{[5-chloro-4-({3- [(methylcarbamoyl) methoxy]- 2-oxo-1-(propan-2- yl)-1,2-dihydroquinolin- 6-yl}amino)pyrimidin-2- yl]amino}ethyl)-N-(2,6- dioxopiperidin-3-::US12310975, Example 373

SMILES CNC(=O)COc1cc2cc(Nc3nc(NCCc4ccc(C(=O)NC5CCC(=O)NC5=O)nc4)ncc3Cl)ccc2n(C(C)C)c1=O

InChI Key InChIKey=VDRMIWXFDBBWNP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743831   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743831BDBM743831(5-(2-{[5-chloro-4-({3- [(methylcarbamoyl) methoxy]...)
Affinity DataIC50: 100nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent