BDBM743854 2-[4-(2-{4-[5-chloro-4- ({1-methyl-3- [(methylcarbamoyl) methoxy]-2-oxo-1,2- dihydroquinolin-6- yl}amino)pyrimidin-2- yl]piperazin-1-yl}propan- 2-yl)piperidin-1-yl]-6- [(2,6-dioxopiperidin-3- yl)carbamoyl]pyridin-1- ium-1-olate::US12310975, Example 396

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCN(C(C)(C)C5CCN(c6cccc(C(=O)NC7CCC(=O)NC7=O)[n+]6[O-])CC5)CC4)ncc3Cl)ccc2n(C)c1=O

InChI Key InChIKey=MDNZSQLUHYWHRS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743854   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743854BDBM743854(2-[4-(2-{4-[5-chloro-4- ({1-methyl-3- [(methylcarb...)
Affinity DataIC50: 30nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent