BDBM743856 2-{[6-({5-chloro-2-[4- ({1-[2-(2,6- dioxopiperidin-3-yl)-1,3- dioxo-2,3-dihydro-1H- isoindol-4-yl]pyrrolidin- 2-yl}methyl)piperazin-1- yl]pyrimidin-4- yl}amino)-2-oxo-1- (propan-2-yl)-1,2- dihydroquinolin-3- yl]oxy}-N- methylacetamide::US12310975, Example 398

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCN(CC5CCCN5c5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)CC4)ncc3Cl)ccc2n(C(C)C)c1=O

InChI Key InChIKey=JHHWDOXFGNRCEO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743856   

TargetB-cell lymphoma 6 protein(Human)
Arvinas Operations

US Patent
LigandPNGBDBM743856(2-{[6-({5-chloro-2-[4- ({1-[2-(2,6- dioxopiperidin...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
Go to US Patent