BDBM743957 2-{[6-({5-chloro-2-[(3S)- 3-({[2-(2,6- dioxopiperidin-3-yl)-1,3- dioxo-2,3-dihydro-1H- isoindol-4- yl]oxy}methyl)piperidin- 1-yl]pyrimidin-4- yl}amino)-1-[2-(oxetan- 3-yl)ethyl]-2-oxo-1,2- dihydroquinolin-3- yl]oxy}-N- methylacetamide::US12310975, Example 504

SMILES CNC(=O)COc1cc2cc(Nc3nc(N4CCC[C@H](COc5cccc6c5C(=O)N(C5CCC(=O)NC5=O)C6=O)C4)ncc3Cl)ccc2n(CCC2COC2)c1=O

InChI Key InChIKey=HKQVCXHRPWLAOC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 743957   

TargetB-cell lymphoma 6 protein(Human)
Arvinas

US Patent
LigandChemical structure of BindingDB Monomer ID 743957BDBM743957(2-{[6-({5-chloro-2-[(3S)- 3-({[2-(2,6- dioxopiperi...)
Affinity DataIC50: 75nMAssay Description:Assay buffer A: 50 mM HEPES pH 7.5, 125 mM NaCl, 0.01% TritonX.Assay buffer B (made fresh): buffer A+1 mM Glutathione (or 0.5 mM DTT).Assay buffer C ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/21/2025
Entry Details
US Patent