BDBM744781 4-(3,3-dimethyl-2,3-dihydro- 1,4-dioxa-5-aza-7- naphthylamino)-2-[p-(3- morpholinopropoxy) phenylamino]pyrimidine::US20250171431, Compound 65

SMILES CC1(C)COc2cc(Nc3ccnc(Nc4ccc(OCCCN5CCOCC5)cc4)n3)cnc2O1

InChI Key InChIKey=UGBBHBSZZYJQAP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 744781   

TargetInsulin-like growth factor 1 receptor(Human)
Horizon Therapeutics Ireland Dac

US Patent
LigandPNGBDBM744781(4-(3,3-dimethyl-2,3-dihydro- 1,4-dioxa-5-aza-7- na...)
Affinity DataIC50: 500nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/23/2025
Entry Details
Go to US Patent