BDBM747026 US20250179047, Example 196

SMILES COCCn1cc(N(C(=O)c2cc(-c3cc4c(cc3C(=O)N3Cc5ccccc5C[C@H]3C)CN(C(=O)Cc3ccc(OCCN5CCOCC5)cc3)CC4)n(C)c2C)c2ccccc2)cn1

InChI Key InChIKey=AWSJKVCJFFTDQR-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 747026   

TargetApoptosis regulator Bcl-2(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM747026(US20250179047, Example 196)
Affinity DataKi:  0.0300nMAssay Description:The assay was performed in a 40 μL volume in white 384-standard well plates (Corning #3574). An 11-point serial dilution of each compound was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2 [D103Y](Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM747026(US20250179047, Example 196)
Affinity DataKi:  0.0900nMAssay Description:The assay was performed in a 40 μL volume in white 384-standard well plates (Corning #3574). An 11-point serial dilution of each compound was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent

TargetApoptosis regulator Bcl-2 [G101V](Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM747026(US20250179047, Example 196)
Affinity DataKi:  2.70nMAssay Description:The assay was performed in a 40 μL volume in white 384-standard well plates (Corning #3574). An 11-point serial dilution of each compound was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent

TargetBcl-2-like protein 1(Human)
Les Laboratoires Servier

US Patent
LigandPNGBDBM747026(US20250179047, Example 196)
Affinity DataKi:  9.60nMAssay Description:The assay was performed in a 40 μL volume in white 384-standard well plates (Corning #3574). An 11-point serial dilution of each compound was prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/30/2025
Entry Details
Go to US Patent