BDBM747683 US12325697, Compound AHU-12

SMILES C#CCOc1ccc(-c2cc(NCC)nc(N3Cc4c(cccc4C(F)(F)F)C3=O)c2)c(-c2nncn2C)c1

InChI Key InChIKey=UQHDXMSTIOXVFS-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 747683   

LigandChemical structure of BindingDB Monomer ID 747683BDBM747683(US12325697, Compound AHU-12)
Affinity DataIC50: 200nMAssay Description:Fluorescein-BODIPY labeled UBED2D(C85K)-Ub was prepared by conjugating ubiquitin (Ub) labeled at its N-terminus with Fluorescein-BODIPY maleimide (Th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/4/2025
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase CBL-C [47-435](Human)
Nimbus Clio

US Patent
LigandChemical structure of BindingDB Monomer ID 747683BDBM747683(US12325697, Compound AHU-12)
Affinity DataIC50: 600nMAssay Description:Recombinant human c-Cbl (aa 47-435) was expressed in E. coli, purified and biotinylated in vitro. The protein was diluted to 12 nM in freshly prepare...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/4/2025
Entry Details
US Patent