BDBM74922 MLS000734704::SMR000317914::[3-(3-chlorobenzyl)-1-[(6-fluoro-2-quinolyl)methyl]-3-piperidyl]methanol::[3-[(3-chlorophenyl)methyl]-1-[(6-fluoranylquinolin-2-yl)methyl]piperidin-3-yl]methanol::[3-[(3-chlorophenyl)methyl]-1-[(6-fluoro-2-quinolinyl)methyl]-3-piperidinyl]methanol::[3-[(3-chlorophenyl)methyl]-1-[(6-fluoroquinolin-2-yl)methyl]piperidin-3-yl]methanol::cid_16188789::{3-(3-chlorobenzyl)-1-[(6-fluoroquinolin-2-yl)methyl]piperidin-3-yl}methanol

SMILES OCC1(Cc2cccc(Cl)c2)CCCN(Cc2ccc3cc(F)ccc3n2)C1

InChI Key InChIKey=JJNLXONZPYBNTJ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 74922   

TargetOrexin/Hypocretin receptor type 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM74922([3-[(3-chlorophenyl)methyl]-1-[(6-fluoroquinolin-2...)
Affinity DataIC50: 5.53E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetOrexin/Hypocretin receptor type 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM74922([3-[(3-chlorophenyl)methyl]-1-[(6-fluoroquinolin-2...)
Affinity DataIC50: 6.33E+3nMAssay Description:Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/3/2011
Entry Details
PCBioAssay
TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM74922([3-[(3-chlorophenyl)methyl]-1-[(6-fluoroquinolin-2...)
Affinity DataEC50: >5.00E+5nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay