BDBM749725 (S)-7-amino-1-(oxazol-2-yl)-7-(5-(quinolin-6-yl)-1H-imidazol-2-yl)heptan-1-one::US12331044, Example 16

SMILES N[C@@H](CCCCCC(=O)C1NC=CO1)C1NC=C(C2C=c3cccnc3=CC2)N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 749725   

TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM749725((S)-7-amino-1-(oxazol-2-yl)-7-(5-(quinolin-6-yl)-1...)
Affinity DataIC50: 2.60nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM749725((S)-7-amino-1-(oxazol-2-yl)-7-(5-(quinolin-6-yl)-1...)
Affinity DataIC50: 2.70nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM749725((S)-7-amino-1-(oxazol-2-yl)-7-(5-(quinolin-6-yl)-1...)
Affinity DataIC50: 8.80nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM749725((S)-7-amino-1-(oxazol-2-yl)-7-(5-(quinolin-6-yl)-1...)
Affinity DataIC50: 1.40E+3nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM749725((S)-7-amino-1-(oxazol-2-yl)-7-(5-(quinolin-6-yl)-1...)
Affinity DataIC50: 3.30E+4nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details