BDBM749732 (S)-7-amino-7-(4-(7-methoxyquinolin-6-yl)-1H-imidazol-2-yl)-1-(oxazol-2-yl)heptan-1-one::US12331044, Example 23

SMILES COC1C=c2ncccc2=CC1C1=CNC([C@@H](N)CCCCCC(=O)C2NC=CO2)N1

InChI Key InChIKey=PUTSJSDLDREGNF-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 749732   

TargetHistone deacetylase 3(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749732((S)-7-amino-7-(4-(7-methoxyquinolin-6-yl)-1H-imida...)
Affinity DataIC50: 1.80nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749732((S)-7-amino-7-(4-(7-methoxyquinolin-6-yl)-1H-imida...)
Affinity DataIC50: 1.90nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749732((S)-7-amino-7-(4-(7-methoxyquinolin-6-yl)-1H-imida...)
Affinity DataIC50: 9.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 8(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749732((S)-7-amino-7-(4-(7-methoxyquinolin-6-yl)-1H-imida...)
Affinity DataIC50: 660nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent

TargetHistone deacetylase 6(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM749732((S)-7-amino-7-(4-(7-methoxyquinolin-6-yl)-1H-imida...)
Affinity DataIC50: 3.10E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/9/2025
Entry Details
Go to US Patent