BDBM749736 (S)-7-amino-7-(5-(7-methoxy-2-methylquinolin-6-yl)oxazol-2-yl)-1-(oxazol-2-yl)heptan-1-one::US12331044, Example 27

SMILES COC1C=c2nc(C)ccc2=CC1C1=CNC([C@@H](N)CCCCCC(=O)C2NC=CO2)O1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 749736   

TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM749736((S)-7-amino-7-(5-(7-methoxy-2-methylquinolin-6-yl)...)
Affinity DataIC50: 1.5nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM749736((S)-7-amino-7-(5-(7-methoxy-2-methylquinolin-6-yl)...)
Affinity DataIC50: 1.90nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM749736((S)-7-amino-7-(5-(7-methoxy-2-methylquinolin-6-yl)...)
Affinity DataIC50: 9.5nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM749736((S)-7-amino-7-(5-(7-methoxy-2-methylquinolin-6-yl)...)
Affinity DataIC50: 1.11E+3nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM749736((S)-7-amino-7-(5-(7-methoxy-2-methylquinolin-6-yl)...)
Affinity DataIC50: 1.20E+3nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details