BDBM749745 (S)-7-amino-7-(5-(2-fluorophenyl)-1H-imidazol-2-yl)-1-(oxazol-4-yl)heptan-1-one::US12331044, Example 36

SMILES N[C@@H](CCCCCC(=O)C1COC=N1)C1NC=C(c2ccccc2F)N1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 749745   

TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM749745((S)-7-amino-7-(5-(2-fluorophenyl)-1H-imidazol-2-yl...)
Affinity DataIC50: 150nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM749745((S)-7-amino-7-(5-(2-fluorophenyl)-1H-imidazol-2-yl...)
Affinity DataIC50: 170nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM749745((S)-7-amino-7-(5-(2-fluorophenyl)-1H-imidazol-2-yl...)
Affinity DataIC50: 740nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 8(Human)TBA
LigandPNGBDBM749745((S)-7-amino-7-(5-(2-fluorophenyl)-1H-imidazol-2-yl...)
Affinity DataIC50: 900nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 6(Human)TBA
LigandPNGBDBM749745((S)-7-amino-7-(5-(2-fluorophenyl)-1H-imidazol-2-yl...)
Affinity DataIC50: 900nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details