BDBM749833 7-amino-7-[2-(4-fluorophenyl)- 2H-1,2,3-triazol-4-yl]-1- isoxazol-3-ylheptan-1-one::US12331044, Example 124

SMILES NC(CCCCCC(=O)c1ccon1)c1cnn(-c2ccc(F)cc2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 749833   

TargetHistone deacetylase 1(Human)TBA
LigandPNGBDBM749833(7-amino-7-[2-(4-fluorophenyl)- 2H-1,2,3-triazol-4-...)
Affinity DataIC50: 450nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 3(Human)TBA
LigandPNGBDBM749833(7-amino-7-[2-(4-fluorophenyl)- 2H-1,2,3-triazol-4-...)
Affinity DataIC50: 480nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
TargetHistone deacetylase 2(Human)TBA
LigandPNGBDBM749833(7-amino-7-[2-(4-fluorophenyl)- 2H-1,2,3-triazol-4-...)
Affinity DataIC50: 1.20E+3nMAssay Description:The HDAC 1, 2 assays employed buffer A, which contained 20 mM HEPES, pH 8.0, 1 mM MgCl2, 137 mM NaCl, 2.7 mM KCl, 0.05% BSA. The HDAC3/SMRT assay emp...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details