BDBM751389 1-(4-(9-benzyl- 6-(1-methyl- cyclopropoxy)- 9H-purin- 8-yl)-3- chlorophenyl) piperidin-4-amine::US20250195530, Example M2

SMILES CC1(Oc2ncnc3c2nc(-c2ccc(N4CCC(N)CC4)cc2Cl)n3Cc2ccccc2)CC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 751389   

TargetDNA polymerase theta(Human)TBA
LigandPNGBDBM751389(1-(4-(9-benzyl- 6-(1-methyl- cyclopropoxy)- 9H-pur...)
Affinity DataIC50: 3.98nMAssay Description:In the assay, Polθ interacts with the substrates (deoxy thymidine triphosphate (dTTP) (Sigma, product code T0251) and a DNA template with a 17-nucleo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details