BDBM752830 US20250197425, Example 6

SMILES CC[C@@H]([C@@H](C)O)Nc1nc(c2c(n1)n(cn2)CC)N[C@H]3CCN(C3)S(=O)(=O)NCC

InChI Key InChIKey=ROGNUCVYDNPNJI-UHFFFAOYSA-N

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 752830   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-D1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 752830BDBM752830(US20250197425, Example 6)
Affinity DataIC50: 9nMAssay Description:Compounds were tested in breast cancer cell line MCF-7 to assess inhibition of CDK1, CDK2, and CDK4 activity. MCF-7 cells transiently transfected wit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/15/2025
Entry Details
US Patent
PDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 752830BDBM752830(US20250197425, Example 6)
Affinity DataIC50: 528nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/15/2025
Entry Details
US Patent

TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Human)
Astrazeneca

US Patent
LigandChemical structure of BindingDB Monomer ID 752830BDBM752830(US20250197425, Example 6)
Affinity DataIC50: 9.40E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/15/2025
Entry Details
US Patent