BDBM754207 (R or S)-2-(4,4-Difluoro-3-methylpiperidin-1-yl)-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide (123) and (S or R)-2-(4,4-difluoro-3-methylpiperidin-1-yl)-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide::US12344595, Example 123

SMILES C[C@H]1CN(c2ncc(C(F)(F)F)cc2C(=O)Nc2cccc(S(N)(=O)=O)c2)CCC1(F)F

InChI Key InChIKey=FZOSCRPHGDDAIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754207   

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM754207((R or S)-2-(4,4-Difluoro-3-methylpiperidin-1-yl)-N...)
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent