BDBM754208 (R or S)-2-(4,4-Difluoro-3-methylpiperidin-1-yl)-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide (123) and (S or R)-2-(4,4-difluoro-3-methylpiperidin-1-yl)-N-(3-sulfamoylphenyl)-5-(trifluoromethyl)nicotinamide::US12344595, Example 124

SMILES C[C@@H]1CN(c2ncc(C(F)(F)F)cc2C(=O)Nc2cccc(S(N)(=O)=O)c2)CCC1(F)F

InChI Key InChIKey=FZOSCRPHGDDAIA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 754208   

TargetSodium channel protein type 10 subunit alpha(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM754208((R or S)-2-(4,4-Difluoro-3-methylpiperidin-1-yl)-N...)
Affinity DataIC50: 15nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent