BDBM755844 3-(1-oxo-5-(6-(pyrrolidin-1- ylmethyl)imidazo[1,5-a]pyridin-3- yl)isoindolin-2-yl)piperidine-2,6- dione::US20250214991, Compound 53

SMILES O=C1CCC(N2Cc3cc(-c4ncc5ccc(CN6CCCC6)cn45)ccc3C2=O)C(=O)N1

InChI Key InChIKey=QTAFXDAVIHODDD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755844   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandChemical structure of BindingDB Monomer ID 755844BDBM755844(3-(1-oxo-5-(6-(pyrrolidin-1- ylmethyl)imidazo[1,5-...)
Affinity DataIC50: 100nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent