BDBM755860 3-(5-(1-methyl-4-((4- (methylsulfonyl)piperazin-1- yl)methyl)-1H-pyrrolo[2,3- b]pyridin-6-yl)-1-oxoisoindolin-2- yl)piperidine-2,6-dione::US20250214991, Compound 61

SMILES Cn6ccc5c(CN1CCN(S(C)(=O)=O)CC1)cc(c4ccc3C(=O)N(C2CCC(=O)NC2=O)Cc3c4)nc56

InChI Key InChIKey=ULDTWZXPOVPWEF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 755860   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandChemical structure of BindingDB Monomer ID 755860BDBM755860(3-(5-(1-methyl-4-((4- (methylsulfonyl)piperazin-1-...)
Affinity DataIC50: 65nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent