BDBM756017 3-(5-(4-((3-isopropylpyrrolidin-1- yl)methyl)-1H-pyrrolo[2,3- b]pyridin-6-yl)-1-oxoisoindolin-2- yl)piperidine-2,6-dione::US20250214991, Compound 146

SMILES CC(C)C1CCN(Cc2cc(-c3ccc4c(c3)CN(C3CCC(=O)NC3=O)C4=O)nc3[nH]ccc23)C1

InChI Key InChIKey=BOFMQMFPERMOIH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 756017   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Oncopia Therapeutics, Inc. D/B/A/ Sk Life Science Labs

US Patent
LigandChemical structure of BindingDB Monomer ID 756017BDBM756017(3-(5-(4-((3-isopropylpyrrolidin-1- yl)methyl)-1H-p...)
Affinity DataIC50: 20nMAssay Description:The binding potency was determined using HTRF assay technology (Perkin Elmer). Compounds were serially diluted in DMSO and 0.2 μL volume was transfer...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/23/2025
Entry Details
US Patent