BDBM756565 US20250215013, Example 3

SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4c(c3)[nH]c(=O)c3cscc34)CC2)c(C)n1

InChI Key InChIKey=VKMZDQDDIAQHOC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756565   

TargetPoly [ADP-ribose] polymerase 1(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 756565BDBM756565(US20250215013, Example 3)
Affinity DataIC50: 1.08nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetProtein cereblon/PARP2(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 756565BDBM756565(US20250215013, Example 3)
Affinity DataIC50: 18.3nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent