BDBM756628 US20250215013, Example 120

SMILES CNC(=O)c1ccc(N2CCN(Cc3cc4[nH]c(=O)n5nccc5c4cc3F)CC2)c(F)n1

InChI Key InChIKey=HRTOLPFSQSROQU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 756628   

TargetPoly [ADP-ribose] polymerase 1(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 756628BDBM756628(US20250215013, Example 120)
Affinity DataIC50: 1.87nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent

TargetProtein cereblon/PARP2(Human)
Impact Therapeutics (Shanghai)

US Patent
LigandChemical structure of BindingDB Monomer ID 756628BDBM756628(US20250215013, Example 120)
Affinity DataIC50: 683nMAssay Description:The solution of recombinant poly(ADP-ribose) polymerase 1 and 2 (PARP1 and PARP2) (40 ng enzyme/well) and the compounds to be tested were mixed, resp...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/26/2025
Entry Details
US Patent