BDBM757376 N-([1,1''-Biphenyl]-2-sulfonyl)-6-(pyrrolidin-1-yl)-1-benzofuran-2-carboxamide::US12357603, Example 45

SMILES O=C(NS(=O)(=O)c1ccccc1-c1ccccc1)c1cc2ccc(N3CCCC3)cc2o1

InChI Key InChIKey=RAVXBHNZQSONAQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757376   

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))
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US Patent
LigandChemical structure of BindingDB Monomer ID 757376BDBM757376(N-([1,1'-Biphenyl]-2-sulfonyl)-6-(pyrrolidin-1-yl)...)
Affinity DataIC50: 1.48E+3nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 757376BDBM757376(N-([1,1'-Biphenyl]-2-sulfonyl)-6-(pyrrolidin-1-yl)...)
Affinity DataIC50: 3.60E+3nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent