BDBM757419 6-(Dimethylamino)-N-(ethanesulfonyl)-1-benzofuran-2-carboxamide::US12357603, Example 61

SMILES CCS(=O)(=O)NC(=O)c1cc2ccc(N(C)C)cc2o1

InChI Key InChIKey=PLANCUFCSSPQDH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757419   

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))
Bayer Aktiengesellschaft

US Patent
LigandChemical structure of BindingDB Monomer ID 757419BDBM757419(6-(Dimethylamino)-N-(ethanesulfonyl)-1-benzofuran-...)
Affinity DataIC50: 9.85E+3nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 757419BDBM757419(6-(Dimethylamino)-N-(ethanesulfonyl)-1-benzofuran-...)
Affinity DataIC50: 1.61E+4nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/28/2025
Entry Details
US Patent