BDBM757494 US12357603, Example 132

SMILES COc1cccc(C(F)(F)F)c1S(=O)(=O)NC(=O)c1cc2ccc(N(C)C)cc2o1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 757494   

TargetHistone acetyltransferase KAT6B [431-2073](Homo sapiens (Human))TBA
LigandPNGBDBM757494(US12357603, Example 132)
Affinity DataIC50: 72.7nMAssay Description:Kat6b was incubated for 30 mins at 22° C. in the presence of different concentrations of test substances (0 μM, and within the range 0.01-20 μM) in a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM757494(US12357603, Example 132)
Affinity DataIC50: 134nMAssay Description:Recombinant human His-tagged Kat6a protein (amino acids 194-810), was purified in-house from Baculovirus-infected insect cells (Sf9). Histone H4 pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details