BDBM759681 (1S,5S)—N-(4-(1-(2,2-difluoroethyl)-3-phenyl-1H-pyrazol-4-yl)-7-methoxyquinazolin-6-yl)-3-oxabicyclo[3.1.0]hexane-1-carboxamide and (1R,5R)—N-(4-(1-(2,2-difluoroethyl)-3-phenyl-1H-pyrazol-4-yl)-7-methoxyquinazolin-6-yl)-3-oxabicyclo[3.1.0]hexane-1-carboxamide::US20250236608, Example 275

SMILES COc4cc3ncnc(c1cn(CC(F)F)nc1c2ccccc2)c3cc4NC(=O)[C@]56COC[C@H]5C6

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 759681   

LigandPNGBDBM759681((1S,5S)—N-(4-(1-(2,2-difluoroethyl)-3-phenyl-1H-py...)
Affinity DataIC50: 1.30nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM759681((1S,5S)—N-(4-(1-(2,2-difluoroethyl)-3-phenyl-1H-py...)
Affinity DataIC50: 1.90nMAssay Description:Inhibitory effects of the compounds of the disclosure were measured in biochemical assays that measure the phosphorylation activity of EGFR enzyme ph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details