BDBM759877 US20250236608, Example 482

SMILES COc1cc2ncnc(-c3c(-c4ccccc4)nn(C)c3C)c2cc1OC(=O)N1CCN(C)C[C@@H]1C

InChI Key InChIKey=YQWTZCLOFDEIJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 759877   

TargetEpidermal growth factor receptor [1-745,751-1210,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759877(US20250236608, Example 482)
Affinity DataIC50: 97nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
11/5/2025
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [L858R,C797S](Human)
Blueprint Medicines

US Patent
LigandPNGBDBM759877(US20250236608, Example 482)
Affinity DataIC50: 207nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
11/5/2025
Entry Details
Go to US Patent