BDBM760581 N-[4-[(6,7-dimethoxy-1,5- naphthyridin-4-yl)oxy]-3- fluorophenyl]-5-(4-fluorophenyl)-6- (methoxymethyl)-1-methyl-4- oxopyridine-3-carboxamide::US12371428, Compound 269
SMILES COCc1c(-c2ccc(F)cc2)c(=O)c(C(=O)Nc2ccc(Oc3ccnc4cc(OC)c(OC)nc34)c(F)c2)cn1C
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 760581
Affinity DataIC50: 100nMAssay Description:Example D-1: Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 M KKKGQEEEYVFIE (SE...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Example C-1: Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIY...More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Example A-1: Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 M KKSRGDYMTMQIG (SEQ ID NO:1), 1...More data for this Ligand-Target Pair
Affinity DataIC50: 300nMAssay Description:Example B-1: Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesiu...More data for this Ligand-Target Pair