BDBM760587 1-(4-fluorophenyl)-N-[3-fluoro-4-[(7- phenylmethoxy-1,5-naphthyridin-4- yl)oxy]phenyl]-6-methyl-2- oxopyridine-3-carboxamide::US12371428, Compound 275

SMILES Cc1ccc(C(=O)Nc2ccc(Oc3ccnc4cc(OCc5ccccc5)cnc34)c(F)c2)c(=O)n1-c1ccc(F)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 760587   

LigandPNGBDBM760587(1-(4-fluorophenyl)-N-[3-fluoro-4-[(7- phenylmethox...)
Affinity DataIC50: 100nMAssay Description:Example C-1: Human Mer (residues R557-E882 with H628Q and R794A, 0.7 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 30 mM NaCl, 250 μM GGMEDIY...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM760587(1-(4-fluorophenyl)-N-[3-fluoro-4-[(7- phenylmethox...)
Affinity DataIC50: 100nMAssay Description:Example A-1: Human Axl (residues H473-A894 with Q764R, 161 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 M KKSRGDYMTMQIG (SEQ ID NO:1), 1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM760587(1-(4-fluorophenyl)-N-[3-fluoro-4-[(7- phenylmethox...)
Affinity DataIC50: 200nMAssay Description:Example B-1: Human KDR (residues K790-V1356, 55 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 0.33 mg/mL myelin basic protein, 10 mM magnesiu...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details
LigandPNGBDBM760587(1-(4-fluorophenyl)-N-[3-fluoro-4-[(7- phenylmethox...)
Affinity DataIC50: 200nMAssay Description:Example D-1: Human Met (residues R974-S1390 with A1209G and V1290L, 3.4 nM) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 M KKKGQEEEYVFIE (SE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
TBA
Entry Details