BDBM760610 N-[4-[(6,7-dimethoxy-1,5- naphthyridin-4-yl)oxy]-3- fluorophenyl]-1-(4-fluoro-2- methylphenyl)-4,6-dimethyl-2- oxopyridine-3-carboxamide::US12371428, Compound 298

SMILES COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)cc(C)n(-c5ccc(F)cc5C)c4=O)cc3F)c2nc1OC

InChI Key InChIKey=SOIGNFXKRGRTBP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 760610   

TargetVascular endothelial growth factor receptor 2(Human)
Exelixis

US Patent
LigandPNGBDBM760610(N-[4-[(6,7-dimethoxy-1,5- naphthyridin-4-yl)oxy]-3...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase Mer(Human)
Exelixis

US Patent
LigandPNGBDBM760610(N-[4-[(6,7-dimethoxy-1,5- naphthyridin-4-yl)oxy]-3...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/10/2025
Entry Details
Go to US Patent

TargetTyrosine-protein kinase receptor UFO(Human)
Exelixis

US Patent
LigandPNGBDBM760610(N-[4-[(6,7-dimethoxy-1,5- naphthyridin-4-yl)oxy]-3...)
Affinity DataIC50: 100nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/10/2025
Entry Details
Go to US Patent

TargetHepatocyte growth factor receptor(Human)
Exelixis

US Patent
LigandPNGBDBM760610(N-[4-[(6,7-dimethoxy-1,5- naphthyridin-4-yl)oxy]-3...)
Affinity DataIC50: 200nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/10/2025
Entry Details
Go to US Patent