BDBM761247 US20250243180, Compound 239

SMILES Cc1nc(CNC(=O)C(C)(C)c2ccccc2)cc(Cl)c1C1CCC(=O)NC1=O

InChI Key InChIKey=HZRZLKDTLLGFCD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 761247   

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Monte Rosa Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 761247BDBM761247(US20250243180, Compound 239)
Affinity DataEC50:  550nMAssay Description:A one pot detection solution of CRBN-DDB1 (2.5 nM), Anti-His Terbium Cryptate Gold (1×, PerkinElmer Cat. #: 61HI2TLB), and Cy5-Thalidomide (100 nM, T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetDNA damage-binding protein 1/Protein cereblon(Human)
Monte Rosa Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 761247BDBM761247(US20250243180, Compound 239)
Affinity DataEC50:  660nMAssay Description:A one pot detection solution of CRBN-DDB1 (2.5 nM), Anti-His Terbium Cryptate Gold (1×, PerkinElmer Cat. #: 61HI2TLB), and Cy5-Thalidomide (100 nM, T...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent