BDBM767614 methyl 2-(5-(6,7-dichloro-3- (1H-pyrazol-4-yl)-1H-indol-2- yl)-4H-1,2,4-triazol-3- yl)acetate::US12404261, Example 29

SMILES COC(=O)Cc1nnc(-c2[nH]c3c(Cl)c(Cl)ccc3c2-c2cn[nH]c2)[nH]1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 767614   

TargetCyclic GMP-AMP synthase(Human)
Novartis

US Patent
LigandChemical structure of BindingDB Monomer ID 767614BDBM767614(methyl 2-(5-(6,7-dichloro-3- (1H-pyrazol-4-yl)-1H-...)
Affinity DataIC50: 218nMAssay Description:A reagent buffer was prepared in filtered and autoclaved water according to the following:50 mM Tris-buffer pH 7.5 (1 M Tris-buffer pH 7.5, Invitroge...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/11/2025
Entry Details
US Patent