BDBM768484 methyl 2-[(4S,5S)-4-(4- fluorophenyl)-3-methyl-6- oxo-1-phenyl-5-[3- (trifluoromethyl) benzamido]- 1H,4H,5H,6H,7H- pyrazolo[3,4-b]pyridin-7- yl]acetate::US12409171, Name RG-0013841

SMILES COC(=O)CN1C(=O)[C@@H](NC(=O)c2cccc(C(F)(F)F)c2)[C@@H](c2ccc(F)cc2)c2c(C)nn(-c3ccccc3)c21

InChI Key InChIKey=WETRGMMPKNRTDV-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 768484   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
University of Kentucky Research Foundation; Memorial Sloan-Kettering Cancer Center; St. Jude Children''s Research Hospital, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 768484BDBM768484(methyl 2-[(4S,5S)-4-(4- fluorophenyl)-3-methyl-6- ...)
Affinity DataEC50:  5.54E+3nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
12/17/2025
Entry Details
US Patent