BDBM768521 ethyl 5-[(4S,5S)-7-ethyl-3- methyl-6-oxo-1-phenyl- 5-[3-(trifluoromethyl) benzamido]- 1H,4H,5H,6H,7H- pyrazolo[3,4-b]pyridin-4- yl]-2-fluorobenzoate::US12409171, Name RG-0014048

SMILES CCOC(=O)c1cc([C@H]2c3c(C)nn(-c4ccccc4)c3N(CC)C(=O)[C@H]2NC(=O)c2cccc(C(F)(F)F)c2)ccc1F

InChI Key InChIKey=AIKJZFDBIUTWIT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 768521   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
University of Kentucky Research Foundation; Memorial Sloan-Kettering Cancer Center; St. Jude Children''s Research Hospital, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 768521BDBM768521(ethyl 5-[(4S,5S)-7-ethyl-3- methyl-6-oxo-1-phenyl-...)
Affinity DataEC50: >3.65E+4nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent