BDBM768554 (2E)-N-[(4S,5S)-7-ethyl-4- (4-fluorophenyl)-3-methyl- 6-oxo-1-phenyl- 1H,4H,5H,6H,7H- pyrazolo[3,4-b]pyridin-5- yl]pent-2-enamide::US12409171, Name RG-0014157

SMILES CC/C=C/C(=O)N[C@@H]1C(=O)N(CC)c2c(c(C)nn2-c2ccccc2)[C@@H]1c1ccc(F)cc1

InChI Key InChIKey=VOAGTHIIMCEXEG-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 768554   

TargetDCN1-like protein 1/NEDD8-conjugating enzyme Ubc12(Human)
University of Kentucky Research Foundation; Memorial Sloan-Kettering Cancer Center; St. Jude Children''s Research Hospital, Inc.

US Patent
LigandChemical structure of BindingDB Monomer ID 768554BDBM768554((2E)-N-[(4S,5S)-7-ethyl-4- (4-fluorophenyl)-3-meth...)
Affinity DataEC50: >3.07E+4nMAssay Description:The TR-FRET assay was carried out in black 384-well microtiter plates at a final volume of 20 μM per well. To screen library compounds, the assay coc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
12/17/2025
Entry Details
US Patent