BDBM773968 5-((1H- pyrazol-1- yl)methyl)-N- ((5-(tert- butyl)-2- methoxyphenyl) sulfonyl)-6- cyclopropyl- picolinamide::US20250304535, Example C8

SMILES COc1ccc(C(C)(C)C)cc1S(=O)(=O)NC(=O)c1ccc(Cn2cccn2)c(C2CC2)n1

InChI Key InChIKey=ZRCHIZKJYMKWCT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 773968   

TargetHistone acetyltransferase KAT6B [657-1069](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 773968BDBM773968(5-((1H- pyrazol-1- yl)methyl)-N- ((5-(tert- butyl)...)
Affinity DataIC50: 100nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent

TargetHistone acetyltransferase KAT6A [497-780](Human)
Beigene Switzerland

US Patent
LigandChemical structure of BindingDB Monomer ID 773968BDBM773968(5-((1H- pyrazol-1- yl)methyl)-N- ((5-(tert- butyl)...)
Affinity DataIC50: 100nMAssay Description:A competitive displacement assay was configured for B-Raf that monitors the amount of a fluorescently-tagged tracer bound to B-Raf via TR-FRET from a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent