BDBM774986 (S)-2-(6-(4-(but-2-ynoyl)piperazin-1-yl)-4-(3-((4-methyl-4H-1,2,4-triazol-3-yl)methyl)oxetan-3-yl)pyridin-2-yl)-6-((3-methylpiperidin-1-yl)methyl)-4-(trifluoromethyl)isoindolin-1-one::US20250304563, Compound 137

SMILES CC#CC(=O)N1CCN(c2cc(C3(Cc4nncn4C)COC3)cc(N3Cc4c(cc(CN5CCC[C@H](C)C5)cc4C(F)(F)F)C3=O)n2)CC1

InChI Key InChIKey=FYRSLRSBDNQUCP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 774986   

LigandChemical structure of BindingDB Monomer ID 774986BDBM774986((S)-2-(6-(4-(but-2-ynoyl)piperazin-1-yl)-4-(3-((4-...)
Affinity DataIC50: 12.5nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/19/2026
Entry Details
US Patent