BDBM780299 4-[[2-(4-fluoro-2-methyl-::US12441703, Compound 4

SMILES Cc1cc(F)ccc1Oc1ccc(C(F)(F)F)cc1C(=O)Nc1ccnc(C(N)=O)c1

InChI Key InChIKey=CZPKTSWMDGGWML-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 780299   

TargetSodium channel protein type 10 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 780299BDBM780299(4-[[2-(4-fluoro-2-methyl- | US12441703, Compound 4)
Affinity DataIC50: 650nMAssay Description:Assay Protocol (7 Key Steps):1) To reach the final concentration in each well, 400 nL of each compound was pre-spotted (in neat DMSO) into polypropyl...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/3/2026
Entry Details
US Patent