BDBM783224 1,6-bis((R)-4- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)-3,3,4- trimethyl-5-oxo- 2,3,4,5-tetrahydro-1H- pyrrolo[3,2-b]pyridin- 1-yl)-2-oxoethyl)-5- methylpiperazin-2- yl)methyl)-3- methylpiperazin-1- yl)hexane-1,6-dione::US20250326771, Compound 32

SMILES C[C@@H]1CN(CC(=O)C2CC(C)(C)c3c2cc(Cc2ccc(F)cc2)c(=O)n3C)[C@@H](CC2CCC(C(=O)CCCCC(=O)N3CCN(C[C@H]4CN[C@H](C)CN4CC(=O)N4CC(C)(C)c5c4cc(Cc4ccc(F)cc4)c(=O)n5C)[C@H](C)C3)CC2)CN1

InChI Key InChIKey=DEKODQXISLRJIX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 783224   

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783224BDBM783224(1,6-bis((R)-4- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [255-322](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783224BDBM783224(1,6-bis((R)-4- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [269-336](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783224BDBM783224(1,6-bis((R)-4- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783224BDBM783224(1,6-bis((R)-4- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)...)
Affinity DataIC50: 2.08E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [169-235](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783224BDBM783224(1,6-bis((R)-4- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)...)
Affinity DataIC50: 6.58E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [184-250](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783224BDBM783224(1,6-bis((R)-4- (((2R,5R)-1-(2-(6-(4- fluorobenzyl)...)
Affinity DataIC50: 6.58E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent