BDBM783308 1,1''-(2,2''- ((3R,3''R,6R,6''R)- (((2S,2''S)-((hexa-2,4- diyne-1,6- diylbis(oxy))bis(methylene)) bis(morpholine- 2,4- diyl))bis(methylene)) bis(3-methylpiperazine- 6,1- diyl))bis(acetyl))bis(6- (4-fluorobenzyl)-3,3,4- trimethyl-1,2,3,4- tetrahydro-5H- pyrrolo[3,2-b]pyridin- 5-one)::US20250326771, Compound 116

SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3c2cc(Cc2ccc(F)cc2)c(=O)n3C)[C@@H](CN2CCO[C@H](COCC#CC#CCOC[C@@H]3CN(C[C@H]4CN[C@H](C)CN4CC(=O)N4CC(C)(C)c5c4cc(Cc4ccc(F)cc4)c(=O)n5C)CCO3)C2)CN1

InChI Key InChIKey=AHUGCLDEIOGAAT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 783308   

TargetBaculoviral IAP repeat-containing protein 2 [269-336](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783308BDBM783308(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-((hexa-2,...)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [255-322](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783308BDBM783308(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-((hexa-2,...)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783308BDBM783308(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-((hexa-2,...)
Affinity DataIC50: 266nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 3 [169-235](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783308BDBM783308(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-((hexa-2,...)
Affinity DataIC50: 6.58E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent

TargetBaculoviral IAP repeat-containing protein 2 [184-250](Human)
Viiv Healthcare

US Patent
LigandChemical structure of BindingDB Monomer ID 783308BDBM783308(1,1'-(2,2'- ((3R,3'R,6R,6'R)- (((2S,2'S)-((hexa-2,...)
Affinity DataIC50: 6.58E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent