BDBM783927 7-fluoro-3-(3-(4-(3-(trifluoro- methoxy)phenyl)piperazin- 1-yl)propyl)isoquinolin- 1(2H)-one::US12459899, Example 16

SMILES O=c1[nH]c(CCCN2CCN(c3cccc(OC(F)(F)F)c3)CC2)cc2ccc(F)cc12

InChI Key InChIKey=GGUDJDQZAFTDCI-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783927   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783927BDBM783927(7-fluoro-3-(3-(4-(3-(trifluoro- methoxy)phenyl)pip...)
Affinity DataIC50: 1nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent