BDBM783928 3-(3-(4-(3- chlorophenyl)piperazin-1- yl)propyl)-7-fluoroisoquinolin- 1(2H)-one::US12459899, Example 17

SMILES O=c1[nH]c(CCCN2CCN(c3cccc(Cl)c3)CC2)cc2ccc(F)cc12

InChI Key InChIKey=QTYSTXOXZCIJDB-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783928   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783928BDBM783928(3-(3-(4-(3- chlorophenyl)piperazin-1- yl)propyl)-7...)
Affinity DataIC50: 1nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent