BDBM783949 2-fluoro-4-(4-(3-(7-fluoro-5- methyl-1-oxo-1,2- dihydroisoquinolin-3- yl)propyl)piperazin-1- yl)benzonitrile::US12459899, Example 38

SMILES Cc1cc(F)cc2c(=O)[nH]c(CCCN3CCN(c4ccc(C#N)c(F)c4)CC3)cc12

InChI Key InChIKey=CBQMDSUYNCLVIL-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783949   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783949BDBM783949(2-fluoro-4-(4-(3-(7-fluoro-5- methyl-1-oxo-1,2- di...)
Affinity DataIC50: 1nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent