BDBM783950 7-fluoro-5-methyl-3-(3-(4-(4- (trifluoromethyl)phenyl) piperazin-1-yl)propyl)iso- quinolin-1(2H)-one::US12459899, Example 39

SMILES Cc1cc(F)cc2c(=O)[nH]c(CCCN3CCN(c4ccc(C(F)(F)F)cc4)CC3)cc12

InChI Key InChIKey=SUZPDCVDYPEOPH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783950   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783950BDBM783950(7-fluoro-5-methyl-3-(3-(4-(4- (trifluoromethyl)phe...)
Affinity DataIC50: 1nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent