BDBM783972 7-fluoro-3-(3-(6-fluoro-3'',6''- dihydro-[3,4''-bipyridine]- 1''(2''H)-yl)propyl)-5- methylisoquinolin-1(2H)-one::US12459899, Example 63

SMILES Cc1cc(F)cc2c(=O)[nH]c(CCCN3CC=C(c4ccc(F)nc4)CC3)cc12

InChI Key InChIKey=BWWMHBFZXVFBJP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783972   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783972BDBM783972(7-fluoro-3-(3-(6-fluoro-3',6'- dihydro-[3,4'-bipyr...)
Affinity DataIC50: 1nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent