BDBM783991 8-fluoro-3-(3-(4-(2- fluorophenyl)-3,6- dihydropyridin-1(2H)-yl)-3- oxopropyl)isoquinolin-1(2H)- one::US12459899, Example 82

SMILES O=C(CCc1cc2cccc(F)c2c(=O)[nH]1)N1CC=C(c2ccccc2F)CC1

InChI Key InChIKey=TVEVLBWWBBZPDF-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 783991   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 783991BDBM783991(8-fluoro-3-(3-(4-(2- fluorophenyl)-3,6- dihydropyr...)
Affinity DataIC50: 1nMAssay Description:The assay buffer used in this screen is 0.05 M acetate, pH 4.2, 10% DMSO final, 100 uM genapol (which is a nonionic detergent, below its Critical Mic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent