BDBM784147 7-(3-(3,6-dihydro-[4,4''- bipyridine]-1(2H)-yl)propyl)- 1,6-naphthyridin-5(6H)-one::US12459899, Example 240

SMILES O=c1[nH]c(CCCN2CC=C(c3ccncc3)CC2)cc2ncccc12

InChI Key InChIKey=APTRNZFFXPOMAR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784147   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784147BDBM784147(7-(3-(3,6-dihydro-[4,4'- bipyridine]-1(2H)-yl)prop...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent