BDBM784151 7-(3-(4-(4-fluorophenyl)-3,6- dihydropyridin-1(2H)-yl)-3- oxopropyl)-1,6-naphthyridin- 5(6H)-one::US12459899, Example 244

SMILES O=C(CCc1cc2ncccc2c(=O)[nH]1)N1CC=C(c2ccc(F)cc2)CC1

InChI Key InChIKey=ISMOZBHMSKZQSC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784151   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784151BDBM784151(7-(3-(4-(4-fluorophenyl)-3,6- dihydropyridin-1(2H)...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent