BDBM784181 4-((8-(3-(8-fluoro-1-oxo-1,2- dihydroisoquinolin-3- yl)propanoyl)-8- azabicyclo[3.2.1]octan-3- yl)oxy)benzonitrile::US12459899, Example 274

SMILES N#Cc1ccc(OC2CC3CCC(C2)N3C(=O)CCc2cc3cccc(F)c3c(=O)[nH]2)cc1

InChI Key InChIKey=TZBFKDJYBGCCHN-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784181   

TargetPoly [ADP-ribose] polymerase 1(Human)
Digmbio

US Patent
LigandChemical structure of BindingDB Monomer ID 784181BDBM784181(4-((8-(3-(8-fluoro-1-oxo-1,2- dihydroisoquinolin-3...)
Affinity DataIC50: 1nMAssay Description:Recombinant Cat D was expressed in CHO cells. The assay buffer for CathepsinD is 0.05 M citrate pH 3.5, 10% DMSO final, 5 mM CHAPS. The Cat D enzyme ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/23/2026
Entry Details
US Patent